Figure 3.

miR-339-5p promotes IR-induced apoptosis of lung cancer cells. (A) A549 and H460 cells were non-transfected (control) or transfected with NC or miR-339-5p mimics. Twenty-four hours later, cells were exposed to 12 Gy of IR or untreated for another 24 h. Cell apoptosis was detected by Annexin V/PI staining and flow cytometry. (B) Mean apoptosis rate assessed by flow cytometry in response to IR exposure as in (A). Mean ±SD of 3 independent experiments were performed (* P<0.05, ** P<0.01).