Table 2.

Rate constants k (s⁻¹) of cis to trans isomerization of (R)-2-8.

Compound	k at 35 °C	k at 45 °C	k at 55 °C	k at 65 °C
(R)-2	4.7 × 10−6	9.8 × 10−6	4.0 × 10−5	1.1 × 10−4
(R)-3	5.9 × 10−6	1.8 × 10−5	5.0 × 10−5	1.4 × 10−4
(R)-4	5.0 × 10−6	1.1 × 10−5	4.6 × 10−5	1.1 × 10−4
(R)-5	3.4 × 10−6	1.8 × 10−5	3.1 × 10−5	8.1 × 10−5
(R)-6	5.7 × 10−6	1.3 × 10−5	2.9 × 10−5	8.5 × 10−5
(R)-7	8.2 × 10−6	2.7 × 10−5	4.5 × 10−5	1.4 × 10−4
(R)-8	5.2 × 10−6	1.4 × 10−5	4.2 × 10−5	1.2 × 10−4

Conditions: 1,4-dioxane, 1.0 × 10⁻⁵ M.