Table 1.
Compd. No. | Percent protection | ||
---|---|---|---|
1 hour | 2 hours | 3 hours | |
Visnagen | 38.6 ± 1.38 * | 40.2 ± 1.39 * | 26.2 ± 1.29 * |
Khellin | 40.3 ± 1.40 * | 41.5 ± 1.42 * | 30.4 ± 1.32 * |
1a | 41.5 ± 1.35 * | 40.4 ±1.36 * | 28.2 ± 1.28 * |
1b | 42.6 ± 1.45 * | 41.5 ±1.28 * | 30.1 ± 1.30 * |
2a | 44.5 ± 1.28 * | 43.6 ±1.24 * | 33.1 ± 1.01 * |
2b | 45.7 ± 1.30 * | 44.8 ±1.28 * | 34.2 ± 1.02 * |
3a | 52.6± 1.10 ** | 50.8 ± 1.30 * | 39.4± 1.25 * |
3b | 48.6 ± 1.40 * | 45.6 ±1.40 * | 35.1 ± 1.04 * |
3c | 52.8± 1.12 ** | 52.6 ± 1.10 * | 39.6± 1.23 * |
3d | 49.9 ± 1.50 ** | 48.8 ±1.42 * | 36.5 ± 1.20 * |
4a | 54.4± 1.23 ** | 53.6 ± 1.22 * | 40.4± 1.04 * |
4b | 53.8± 1.20 ** | 52.6 ± 1.10 * | 40.1± 1.02 * |
4c | 55.3 ± 1.25 ** | 54.8 ± 1.24 * | 40.6± 1.05 * |
4d | 54.1± 1.22 ** | 53.2 ± 1.20 * | 40.2± 1.03 * |
5a | 57.9 ± 1.39 ** | 58.9 ± 1.30 * | 41.5 ± 1.08 * |
5b | 57.3 ± 1.37 ** | 58.8 ± 1.29 * | 41.3± 1.06 * |
5c | 58.4 ± 1.40 ** | 59.1 ± 1.31 ** | 42.1 ± 1.23 * |
5d | 57.6 ± 1.38 ** | 60.0 ± 1.68 ** | 41.4 ± 1.07 * |
6a | 59.7 ± 1.45 ** | 59.5 ± 1.35 ** | 42.8 ± 1.26 * |
6b | 59.4 ± 1.05 ** | 59.1 ± 1.31 ** | 42.2 ± 1.24 * |
6c | 59.8 ± 1.52 ** | 59.7 ± 1.45 ** | 45.7 ± 1.52 * |
6d | 59.6 ± 1.41 ** | 59.2 ± 1.32 ** | 42.4 ± 1.25 * |
7a | 61.8± 1.88 ** | 61.4 ± 1.74 ** | 48.2 ± 1.65 * |
7b | 60.5± 1.80 ** | 60.2 ± 1.62 ** | 46.6 ± 1.60 * |
7c | 62.3± 1.92 ** | 61.6 ± 1.78 ** | 48.5 ± 1.68 * |
7d | 60.9± 1.85 ** | 60.4 ± 1.65 ** | 47.1 ± 1.63 * |
Control | 6.3 ± 0.26 | 5.6 ± 0.40 | 3.4 ± 0.96 |
Diclofenac Sodium | 52.6 ± 0.96 * | 60.5± 1.55 ** | 42.2 ± 1.39 * |
Each value represents the mean ± S.E (n = 6).Significance levels * p < 0.5, ** p < 0.001 as compared with respective control. Dose (20 mg/kg). For the selected tested compound.