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. 2011 Feb 25;16(3):1956–1972. doi: 10.3390/molecules16031956

Table 1.

Percent anti-inflammatory activity of the tested compounds (carrageenan-induced paw edema test in rats).

Compd. No. Percent protection
1 hour 2 hours 3 hours
Visnagen 38.6 ± 1.38 * 40.2 ± 1.39 * 26.2 ± 1.29 *
Khellin 40.3 ± 1.40 * 41.5 ± 1.42 * 30.4 ± 1.32 *
1a 41.5 ± 1.35 * 40.4 ±1.36 * 28.2 ± 1.28 *
1b 42.6 ± 1.45 * 41.5 ±1.28 * 30.1 ± 1.30 *
2a 44.5 ± 1.28 * 43.6 ±1.24 * 33.1 ± 1.01 *
2b 45.7 ± 1.30 * 44.8 ±1.28 * 34.2 ± 1.02 *
3a 52.6± 1.10 ** 50.8 ± 1.30 * 39.4± 1.25 *
3b 48.6 ± 1.40 * 45.6 ±1.40 * 35.1 ± 1.04 *
3c 52.8± 1.12 ** 52.6 ± 1.10 * 39.6± 1.23 *
3d 49.9 ± 1.50 ** 48.8 ±1.42 * 36.5 ± 1.20 *
4a 54.4± 1.23 ** 53.6 ± 1.22 * 40.4± 1.04 *
4b 53.8± 1.20 ** 52.6 ± 1.10 * 40.1± 1.02 *
4c 55.3 ± 1.25 ** 54.8 ± 1.24 * 40.6± 1.05 *
4d 54.1± 1.22 ** 53.2 ± 1.20 * 40.2± 1.03 *
5a 57.9 ± 1.39 ** 58.9 ± 1.30 * 41.5 ± 1.08 *
5b 57.3 ± 1.37 ** 58.8 ± 1.29 * 41.3± 1.06 *
5c 58.4 ± 1.40 ** 59.1 ± 1.31 ** 42.1 ± 1.23 *
5d 57.6 ± 1.38 ** 60.0 ± 1.68 ** 41.4 ± 1.07 *
6a 59.7 ± 1.45 ** 59.5 ± 1.35 ** 42.8 ± 1.26 *
6b 59.4 ± 1.05 ** 59.1 ± 1.31 ** 42.2 ± 1.24 *
6c 59.8 ± 1.52 ** 59.7 ± 1.45 ** 45.7 ± 1.52 *
6d 59.6 ± 1.41 ** 59.2 ± 1.32 ** 42.4 ± 1.25 *
7a 61.8± 1.88 ** 61.4 ± 1.74 ** 48.2 ± 1.65 *
7b 60.5± 1.80 ** 60.2 ± 1.62 ** 46.6 ± 1.60 *
7c 62.3± 1.92 ** 61.6 ± 1.78 ** 48.5 ± 1.68 *
7d 60.9± 1.85 ** 60.4 ± 1.65 ** 47.1 ± 1.63 *
Control 6.3 ± 0.26 5.6 ± 0.40 3.4 ± 0.96
Diclofenac Sodium 52.6 ± 0.96 * 60.5± 1.55 ** 42.2 ± 1.39 *

Each value represents the mean ± S.E (n = 6).Significance levels * p < 0.5, ** p < 0.001 as compared with respective control. Dose (20 mg/kg). For the selected tested compound.