. 2011 Mar 9;16(3):2304–2312. doi: 10.3390/molecules16032304

Table 3.

Antibacterial activities of newly synthesized compounds 3–5.

Compound	X	Y	Staphylococcus aureus	Escherichia coli
3a	NO₂	Me	+ + +	+ + +
3b	NO₂	NO₂	+ + +	+ + +
4a	NO₂	Me	+ + +	+ + +
4b	NO₂	NO₂	+ + +	+ + +
5a	NO₂	―	+ + +	+ + +
3e	OMe	Me	+ +	+
4c	H	H	+ +	+
4e	OMe	Me	+ +	+
4f 3c 3d 3f 4d 5b 5c	OMe H H OMe H H OMe	H H Me H Me ― ―	+ + ― ― ― ― ― ―	+ ― ― ― ― ― ―

+ + + for maximum activity, MIC = 25 μg/mL; + + for moderate activity, MIC = 50 μg/mL; +for slight activity, MIC = 75 μg/mL and – for inactive.