Table 2.

An informatics research agenda

Informatics Research Opportunities	Subtopics
Develop data standards	Develop data and meta-data
Produce new datasets	Capture journal club and conference appraisal data
	Leverage electronic health record for data-driven appraisal
	Automate appraisal
Aggregate existing datasets	Published literature (eg, journal comments, reviews, meta-research, article introductions)
	Unindexed sources (eg, PPPR platforms, social media)
Develop appraisal ontology	Domain expert–driven
	Annotation-derived development
	Text-based concept detection
Expand tools and platforms	Researcher and practitioner engagement
	Patient and research participant engagement
	Retrieval tool development
	Recommendation system development
	Visualization tool development
Research appraisal knowledge	Methodology development
	Quality assessment
	Outcomes research
Enable other translational research	Study design, planning, and prioritization
	Trial methods development
	Novel application to nontraditional evidence sources
	Meta-research
	Systematic review development
	Practice/policy guideline development
Provide leadership and incentives	Working group formation
	Career, social, and financial incentivization for appraisal production
	Cultural norms for appraisal production and uptake
	Research funding
	Infrastructure development