Table 1.

Activity of plant phenolics against Streptococcus mutans.

N.	Name	Mol. weight	Plant name	Part of the plant	Activity against S. mutans	References
1	Xanthorrhizol	218.3	Curcuma xanthorrihiza Roxb	rhizome	5 mmol L−1 inhibit biofilm formation	[49]
2	Bakuchiol	256.4	Psoralea corylifolia L.	seeds	20 µg/mL prevented growth	[50]
3	Macelignan	328.4	Myristica fragrans Houtt.	seeds	10 μ/mL for 30’ exposure removed >50% of primary biofilm formed by S. mutans, S. sanguinis and A . viscosus	[51]
4	Malvin	655.2	Alcea longipedicellata I. Riedl	flowers	M.I.C. 0.16 mg/mL for S. mutans	[52]
5	Kuwanon G	692.7	Morus alba L.	Root bark	M.I.C. 8 μg/mL	[53]
6	(−)-Cubebin	356.4	Piper cubeba L.	seeds	M.I.C. 0.32 mM	[54]
7	Guaijaverin		Psidium guaiava L.	leaves	M.I.C. 4 mg/mL	[55]
8	Magnolol	266.3	Magnolia officinalis	bark	0.32 mg/mL reduced by 87.3% GTF activity	[56]
9	Honokiol	266.3	Magnolia officinalis	bark	0.32 mg/mL reduced by 58.1% GTF activity	[56]
10	Dihydrobiochanin A	286.3	Swartzia polyphylla DC	heartwood	M.I.C. 50 µg/mL	[65]
11	Ferreirin	302.3	Swartzia polyphylla DC	heartwood	M.I.C. 50 µg/mL	[65]
12	Dihydrocajanin	302.3	Swartzia polyphylla DC	heartwood	M.I.C. 100 µg/mL	[65]
13	Dalbergioidin	288.3	Swartzia polyphylla DC	heartwood	M.I.C. 100 µg/mL	[65]
14	Lavandulylflavanone	438.5	Sophora exigua Craigg	heartwood	Growth inhibition in the range 1.56–6.25 µg/mL	[66]
15	Artocarpin	436.5	Artocarpus heterophyllus Lam.	heartwood	M.I.C. 6.25 µg/mL	[67]
16	Artocarpesin	354.4	Artocarpus heterophyllus Lam.	heartwood	M.I.C. 6.25 µg/mL	[67]
17	Erycristagallin	392.5	Erythrina variegata L.	root	M.I.C. 6.25 µg/mL	[68]
18	Luteolin	286.2	Perilla frutescens Britton var. japonica Hara.	seeds	M.I.C. 50–100 µg/mL (on different S. mutans strains)	[69]
19	Quercetin	302.2	Commercial source	-	Inhibition of adhesive glucan format ion in the range 1.5–50 µg/mL	[73]
20	Proanthocyanidins	/	Humulus lupulus L.	bracts	0.01%, Hop Bracts Polyphenols (HBP) containing 35% proanthocyanidins caused 80% inhibition of GTF	[79]
21	Tannins	/	Areca catechu L.	nut	50% of growth inhibition at a 15% concentration	[82]
22	Quercetin-3-arabinofuranoside	434.3	Vaccinium macrocarpon Ait.	fruit	21–41% Inhibition of GTF activity at500 mmol L−1	[82]
23	Myricetin	318.0	Vaccinium macrocarpon Ait.	fruit	15-28% Inhibition of GTF activity at500 mmol L−1	[82]
24	Procyanidin A2	576.1	Vaccinium macrocarpon Ait.	fruit	21–41% Inhibition of GTF activity at500 mmol L−1	[82]
25	Theaflavin	564.1	Camellia sinensis L.	leaves	Inhibition of GTF activity in the range 1–10 mM	[85]
26	Theaphlavin monogallate A	716.3	Camellia sinensis L.	leaves	Inhibition of GTF activity in the range 1–10 mM	[85]
27	Theaphlavin monogallate B	716.3	Camellia sinensis L.	leaves	Inhibition of GTF activity in the range 1–10 mM	[85]
28	Theaphlavin digallate	868.1	Camellia sinensis L.	leaves	Inhibition of GTF activity in the range 1–10 mM	[85]
29	Epigallocathechin gallate	458.4	Camellia sinensis L.	leaves	167 mg/L caused 91% growth inhibition*	[85]

M.I.C. = Minimum Inhibition Concentration. GTF = Glucosyltransferases.