Table 1.
CC50 values for LLMCK2 cells and IC50 values for epimastigote form of Trypanosoma cruzi and theirs respective selectivity indexes (SI).
| LLMCK2 CC50 | Epimastigote IC50 | ||
|---|---|---|---|
| μM ± SDb | SIa | ||
| 1 | 59.5 ± 0.1 | 101.7 ± 0.0 | 0.6 |
| 2 | 52.0 ± 0.3 | 58.2 ± 0.2 | 0.9 |
| 3 | 103.4 ± 0.7 | 43.4 ± 5.6 | 2.4 |
| 4 | 71.4 ± 0.7 | 107.0 ± 13.0 | 0.7 |
| 5 | 31.1 ± 1.0 | 68.2 ± 11.2 | 0.5 |
| 6 | 122.4± 1.0 | 23.4 ± 7.7 | 7.3 |
| 7 | 78.2 ± 0.0 | 16.0 ± 4.4 | 5.7 |
| 8 | 29.5 ± 0.8 | 18.3 ± 4.0 | 1.9 |
| 9 | 248.5 ± 0.6 | 79.5 ± 17.9 | 3.2 |
| 10 | 17.1 ± 0.1 | 2.0 ± 1.1 | 9.0 |
| 11 | 104.8 ± 0.4 | 19.0 ± 0.0 | 5.6 |
| 12 | 15.2 ± 0.0 | 116.6 ± 12.8 | 0.1 |
| 13 | 364.2 ± 11.3 | 39.4 ± 14.3 | 8.4 |
| 14 | 56.2 ± 0.4 | 23.5 ± 7.0 | 3.2 |
| 15 | 28.7 ± 1.1 | 14.9 ± 0.3 | 2.0 |
a SI: CC50 LLMCK2 / IC50 epimastigote; b SD: Standard Deviation