Fig. 4 A-D.

Sex- and age-dependent reference values for center-edge angle and alpha angle based on fractional polynomials are shown. Reference values of center-edge angle for women (A) and men (B) increase with age. The formulas for women are 10.04 + 0.181 × age for the lower limit and 31.68 + 0.241 × age for the upper limit. For men, the lower limit is calculated by 11.91 + 0.116 × age and the upper limit by 32.15 + 0.223 × age. The adjusted reference values for alpha angle increase for women (C, formula lower limit: 37.19 + 0.080 × age, upper limit 60.31 + 0.110 × age), whereas they stay nearly steady for men (D, formula lower limit 43.99 + 0.008 × age, upper limit of 74.58 + 0.036 × age). All reference values are given with corresponding 95% CIs.