Table 1.
Comparison between studied groups as regard mean serum level of endocan and VEGF
| Variables | Group I Cirrhosis with HCC (N=105) |
Group II Cirrhosis without HCC (N=90) |
Group III Control (N=60) |
Test (KWT) | P-value |
|---|---|---|---|---|---|
|
| |||||
| Endocan (pg/mL), mean ± SD (range) | a,b4,257.6±847.6 (3,145.0–5,708.0) | a2,099.±459.6 (1,371.0–2,789.0) | 412.6±176.6 (135.6–854.5) | 206.1 | <0.001 (HS) |
| VEGF (pg/mL), mean ± SD (range) | a2,180.8±1,621.4 (621.0–5,104.0) | a1,605.3±4,082.4 (58.0–22,344.0) | 561.0±251.7 (225.9–1,098.0) | 75.6 | <0.001 (HS) |
Notes:
a
Significant in comparison with controls.
b
Significant in comparison with cirrhosis without HCC. The bold values indicate highly statistical significance.
Abbreviations: HCC, hepatocellular carcinoma; HS, highly significant; KWT, Kruskal–Wallis test; VEGF, vascular endothelial growth factor.