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. 2018 Jan 29;118(2):298–308. doi: 10.1160/TH17-04-0249

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This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 1 — Genome-wide association analyses of intact TAFI. ( A ) Manhattan plot of associations. Dotted line shows genome-wide significance (5 × 10 ⁻⁸ ). ( B ) QQ-Plot. ( C ) Regional association plot of chromosome 13, CPB2 locus. ( D ) Regional association plot of CPB2 locus in a conditional analysis adjusted for the lead SNP, rs56734909. ( E ) Regional association plot in a further conditional analysis adjusted for rs56734909 and rs1087.