Table 1.
Parameter | Parameters Used in Subroutine PRIOR, Mean ± SD |
10000 Simulated Subjects, Mean ± SD |
---|---|---|
Clearance, L/h | 1.16 ± 0.73 | 1.14 ± 0.82 |
Volume, L | 10.50 ± 3.15 | 10.50 ± 1.79 |
Absorption constant, h-1 | 5.40 ± 2.11 | 5.40 ± 1.58 |
TLag, h | 0.46 ± 0.45 | 0.47 ± 0.67 |
Peak, mg/L, for 250 mg | … | 22.25 ± 3.73 |
Abbreviations: SD, standard deviation; TLag, Time lag.