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. 2018 Nov 28;67(Suppl 3):S308–S316. doi: 10.1093/cid/ciy624

Table 1.

d-Cycloserine Pharmacokinetic Parameters and Variances

Parameter Parameters Used in Subroutine PRIOR,
Mean ± SD
10000 Simulated Subjects,
Mean ± SD
Clearance, L/h 1.16 ± 0.73 1.14 ± 0.82
Volume, L 10.50 ± 3.15 10.50 ± 1.79
Absorption constant, h-1 5.40 ± 2.11 5.40 ± 1.58
TLag, h 0.46 ± 0.45 0.47 ± 0.67
Peak, mg/L, for 250 mg 22.25 ± 3.73

Abbreviations: SD, standard deviation; TLag, Time lag.