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. 2018 Apr 27;67(12):1897–1903. doi: 10.1093/cid/ciy372

Table 2.

Performance Comparison of the Techniques (QUIK CHEK®, ELISA and qPCR) in Detecting Cryptosporidium spp.

Methods Comparison
(n = 832)
Sensitivity Specificity PPV NPV Agreement Analysis
QUIK CHEK vs ELISAa 96.7% 99.0% 78.4% 99.9% κ = 0.860 (P < .0001)
QUIK CHEK vs qPCRa 50.0% 100.0% 100% 95.3% κ = 0.646 (P < .0001)
ELISA vs qPCRa 40.5% 100.0% 100% 94.5% κ = 0.554 (P < .0001)

Abbreviations: ELISA, enzyme-linked immunosorbent assay; NPV, negative predictive value; PPV, positive predictive value; qPCR, quantitative polymerase chain reaction.

aGold standard.