Table 1.
Univariate and multivariate Cox regression analyses for DFS among patients diagnosed with BC with and without PD
| Variable | Crude HR | 95% CI | P-value | Adjusted HR | 95% CI | P-value |
|---|---|---|---|---|---|---|
| Age | ||||||
| <40 | 1 | |||||
| ≥40 | 2.25 | 0.30–16.64 | 0.427 | |||
| Diagnosis | ||||||
| DCIS | 1 | |||||
| IDC | 25.98 | 0.12–5,428.72 | 0.232 | |||
| TNM stage | ||||||
| 0 + I + II | 1 | 1 | ||||
| III | 4.965 | 2.22–11.10 | <0.01 | 7.38 | 3.24–16.86 | <0.01 |
| Hormone receptor | ||||||
| Negative | 1 | 1 | ||||
| Positive | 0.14 | 0.04–0.47 | 0.001 | 0.22 | 0.06–0.76 | 0.018 |
| HER2 | ||||||
| Negative | 1 | 1 | ||||
| Positive | 3.44 | 1.37–8.64 | 0.009 | 2.72 | 1.04–7.06 | 0.040 |
| PD | ||||||
| Without | 1 | 1 | ||||
| With | 4.96 | 1.84–13.35 | 0.002 | 2.96 | 1.04–8.47 | 0.043 |
Note: Bold-faced values are statistically significant (P<0.05).
Abbreviations: BC, breast cancer; DCIS, ductal carcinoma in situ; DFS, disease-free survival; HR, hazards ratio; IDC, invasive ductal carcinoma; PD, Paget’s disease.