Figure 2.

Multibody effect in ATP hydrolysis plotted as a ratio of the conditional rate with the average rate for specific combinations of nucleotide states of neighboring subunits. Combinations of neighboring subunit states are indicated using a key on the x axis that denotes the state (0 = unhydrolyzed, 1 = hydrolyzed) of each of the neighboring subunits, starting from the third neighbor toward the pointed end to the third neighbor toward the barbed end. Error bars indicate the standard error for each data point and are smaller than the symbol size for most of the data. To see this figure in color, go online. See Fig. S5b for data corresponding to all 64 possible combinations.