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. 2018 Sep 1;115(8):1589–1602. doi: 10.1016/j.bpj.2018.08.034

Table 1.

Macroscopic Rate Constants Used in the Kinetic Models

Model reference Kpol. (μM−1s−1)
Kdis., barbed (s−1)
Kdis., pointed (s−1)
Khyd. (s−1) Krel. (s−1)
barbed pointed ATP ADP-Pi ADP ATP ADP
(34) 11.6 1.4 1.1 7.2 0.3 (34) 0.004
(47) 11.6 1.4 7.2 0.8 0.27 0.003

Kpol. is the polymerization rate constant, Kdis., barbed is the depolymerization rate constant at the barbed end, and Kdis., pointed is that at the pointed end. Khyd. and Krel. are rate constants of ATP hydrolysis and Pi release, respectively.