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Sixty-year-old male with intravascular large B-cell lymphoma. Hematoxylin-eosin (H&E) stain of right middle lobe excisional lung biopsy at 20× magnification (A) and 40× magnification (B) demonstrate atypical lymphocytes within the lumen of a pulmonary artery (long arrow) and within surrounding capillary beds (short arrows). CD-20 immunohistochemical stain (C) demonstrates that the atypical lymphocytes stain positive for CD-20 (arrow).
