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. 2018 Nov 14;12(2):269–281. doi: 10.1016/j.tranon.2018.09.015

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© 2018 Published by Elsevier Inc. on behalf of Neoplasia Press, Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Characterization of liposarcoma patient-derived xenograft.

(A) Representation of STRs in patient tumors and corresponding tumor xenografts. Each locus was selected from locations of human chromosomes. (B) Paired copy number analyses of patient tumors (parental) and patient-derived tumor xenografts (Xeno-G1, G2, G3). (C) IHCof patient and tumor xenografts was compared and evaluated for the expression of CDK4 and MDM2. Primary tumor (Xeno-G0), xenografted F1 tumor (Xeo-G1), xenografted F2 (Xeno-G2), and xenografted F3 (Xeno-G3).