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. 2018 Jul 25;26(8):1185–1191. doi: 10.1016/j.jsps.2018.07.007

Table 3.

Robustness and ruggedness studies of the developed method.

Robustness (SD)*
Factor Guaiacol 4-Aminophenol Paracetamol Guaifenesine Sodium benzoate Oxomemazine
1- amount of the used buffer (±0.05 mL) 0.45 1.03 1.10 0.89 1.34 1.15
2- saturation time (±5 min) 0.62 0.98 0.35 0.25 1.25 0.94



Ruggedness (SD)*
1-Two analysts 0.12 0.09 0.46 0.29 0.19 0.15
*

SD: SD of the change in Rf value of each component.