Figure 4.

The population of cytokine-producing T cells in the MLN of IL-33- and PBS-treated mice with DSS-induced colitis was analyzed by flow cytometry. (a) The frequencies and the absolute numbers of CD4⁺IL-17A⁺ and CD4⁺IL-17A⁺IFN-γ⁺ T cells in the MLN of IL-33- and PBS-treated mice with DSS-induced chronic colitis. (b) The absolute numbers of cytokine-producing CD4⁺IL-17A⁺ and CD4⁺IL-17A⁺IFN-γ⁺ T cells of the MLN with and without stimulation. Data indicate mean ± SD of each group (n = 3/group) obtained from a representative of three independent experiments. Statistically significant differences are shown (^∗p < 0.05, ^∗∗p < 0.01).