Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Thermal shift assay of wildtype and p.Q188R GALT
| Melting temperature (Tm, °C) | ||
|---|---|---|
| Wildtype GALT | p.Q188R GALT | |
| None | 55.8 ± 0.2 | 54.6 ± 0.2 |
| Arginine | 54.8 ± 0.1 | 54.7 ± 0.4 |
| Galactose | 58.1 ± 0.4 | 56.0 ± 0.3 |
Comparison of temperature at which half the protein was unfolded (melting temperature, Tm) with no added ligand, arginine (10 mM) or galactose (10 mM). Values presented are the mean values of three replicates
