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. 2018 Nov 26;17:435. doi: 10.1186/s12936-018-2590-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Correlation between plasma concentration of cytokines with disease parameters in children with CM. A heatmap representing the correlation between different cytokines with other variables associated with acute CM (n = 195) such as parasitaemia levels, age, length of coma and brain swelling in Malawian children. Circle size and darkness signify increased positive correlation (shade of colour is proportional to the probability of dependence between variables from + 1 to − 1)