Table 3.
Clinical characteristics of Breast Cancer by tumor subtype (2000–2015)
| Total n = 3451 |
Luminal A n = 863 |
Luminal B n = 122 |
HER-2+ n = 76 |
Triple Neg n = 193 |
Unclassified n = 2197 |
Statistical test | |
|---|---|---|---|---|---|---|---|
| Overall % | 100% | 25.00% | 3.50% | 2.20% | 5.60% | 63.70% | |
| % by subtype | 68.80% | 9.70% | 6.10% | 15.40% | – | ||
| Age mean years (SD) | 60.5 (12.8) | 63 (12.4) | 61 (12.4) | 61 (12.8) | 60 (13.5) | 59 (12.8) | < 0.05a |
| Location | |||||||
| Central | 40 (1.2%) | – | – | – | – | 40 (1.8%) | |
| East | 26 (0.8%) | 11 (1.27%) | 4 (3.28) | – | 5 (2.6%) | 6 (0.3) | |
| North | 11 (0.3%) | 3 (0.4%) | – | – | 3 (1.6%) | 5 (0.2%) | |
| South | 2979 (86.3%) | 748 (86.7%) | 108 (88.5%) | 60 (79.0%) | 154 (79.8%) | 1909 (86.9%) | |
| West | 395 (11.4%) | 101 (11.7%) | 10 (8.2%) | 16 (21.1%) | 31 (16.1%) | 237 (10.8%) | |
| Missing | – | – | – | – | – | – | |
| Grade | < 0.001b | ||||||
| G1 | 297 (11.4%) | 142 (20%) | 8 (7.3%) | 3 (4.9%) | 4 (2.5%) | 140 (9.0%) | |
| G2 | 1640 (63.1%) | 452 (63.7%) | 74 (67.3%) | 36 (59.0%) | 57 (35.0%) | 1021 (65.7%) | |
| G3 | 660 (25.4%) | 116 (16.3%) | 28 (25.5%) | 22 (36.1%) | 102 (62.6%) | 392 (25.2%) | |
| Missing | 854 | 153 | 12 | 15 | 30 | 644 | |
| Tumor size | < 0.05b | ||||||
| < 1 cm | 500 (31.4%) | 135 (36.2%) | 15 (31.9%) | 14 (36.8%) | 18 (21.4%) | 318 (30.2%) | |
| 1-2 cm | 468 (29.4%) | 144 (38.6%) | 15 (31.9%) | 10 (26.3%) | 30 (35.7%) | 269 (25.6%) | |
| 2-5 cm | 518 (32.5%) | 83 (22.3%) | 15 (31.9%) | 13 (34.2%) | 31 (36.9%) | 376 (35.7%) | |
| > 5 cm | 108 (6.8%) | 11 (2.9%) | 2 (4.3%) | 1 (2.6%) | 5 (5.9%) | 89 (8.5%) | |
| Missing | 1857 | 490 | 75 | 38 | 109 | 1145 | |
| Stage | < 0.001b | ||||||
| G1 | 102 (44.7%) | 48 (53.3%) | 2 (22.2%) | 4 (26.7%) | 11 (39.2%) | 37 (43.0%) | |
| G2 | 102 (44.7%) | 37 (41.1%) | 6 (66.7%) | 8 (53.3%) | 11 (39.2%) | 40 (46.5%) | |
| G3 | 23 (10.1%) | 5 (5.6%) | 1 (11.1%) | 3 (20.0%) | 5 (17.9%) | 9 (10.5%) | |
| G4 | 1 (0.4%) | – | – | – | 1 (3.6%) | – | |
| Missing | 3223 | 773 | 113 | 61 | 165 | 2111 | |
| Cancer type | < 0.001b | ||||||
| Invasive | 319 (9.9%) | 80 (9.5%) | 6 (5.0%) | 1 (1.4%) | 8 (4.6%) | 224 (11.1%) | |
| Carcinoma In-situ | 769 (23.8%) | 164 (19.6%) | 31 (25.8%) | 18 (24.7%) | 20 (11.4%) | 536 (26.5%) | |
| Invasive/In-situ | 2131 (66.0%) | 594 (70.9%) | 83 (69.2%) | 54 (74.0%) | 147 (84.0%) | 1253 (62.0%) | |
| Other | 8 (0.2%) | – | – | – | – | 8 (0.4%) | |
| Missing | 224 | 25 | 2 | 3 | 18 | 176 | |
aSignificance obtained from ANOVA test statistic, bSignificance obtained from Chi-Square test statistic