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. 2018 Nov 26;15:328. doi: 10.1186/s12974-018-1357-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Quantification of TH+ expression in SNpc and striatum. a Representative images from TH immunolabeling in SNpc and striatum (magnification × 10, scale bar = 100 μm). b Quantification of TH+ cells/mm³ in SNpc. Results show that MPTP (****p < 0.0001), MPTP+PA (****p = 0.0001), MPTP+NAC (***p = 0.0006), and MPTP+PA + NAC (****p < 0.0001) have a significant decrease of TH+ cells/mm³ compared to their No-MPTP groups. c Measurement of TH+ expression in striatal fibers. All MPTP mice have a significant decrease compared with their respective control groups: MPTP (***p = 0.0007), MPTP+PA (***p = 0.0004), MPTP+NAC (*p = 0.0143), and MPTP+NAC + PA (*p = 0.0396)