Table 2.
Clinical and immunological outcome of children on ART during 24 months of follow-up
| Laboratory parameters | Baseline (n = 393) | 6 months (n = 340) | 12 months (n = 323) | 24 months (n = 234) |
|---|---|---|---|---|
| Mean (SD) hemoglobin (g/dl) | 10.60 (1.64) | 11.33 (1.46) | 11.63 (1.44) | 11.8 (1.3) |
| Mean (SD) CD4% | 16.24 (7.93) | 26.67 (9.54) | 29.31 (9.47) | 35.38 (36)$ |
| Anthropometry n (%) | n = 393 | n = 340 | n = 323 | n = 218 |
| WAZ score < − 2 | 225 (57) | 119 (35) | 71 (22)* | 16 (7)$ |
| HAZ score < − 2 | 205 (52) | 112 (33) | 69 (21)* | 17 (8)$ |
| WHZ score < − 2 | 68 (17) | 35 (10) | 27 (8)* | 23 (11)$ |
| CD4% | n (%) = 345 | n (%) = 284 | n (%) = 243 | n (%) = 135 |
| < 25% | 278 (81) | 117 (41) | 75 (31)* | 33 (24)$ |
| > 25% | 67 (19) | 170 (60) | 168 (69)* | 102 (76)$ |
| CD4 cell count (> 5 years of age) | n (%) = 304 | n = 273 | n = 261 | n = 193 |
| > 350 cells/mm3 | 152 (50) | 245 (90) | 238 (91)* | 176 (91)$ |
| < 350 cells/mm3 | 152 (50) | 28 (10) | 28 (11)* | 17 (9)$ |
| Viral load (copies/ml) | n (%) = 389 | n (%) = 348 | n (%) = 328 | n (%) = 218 |
| < 400 | 11 (3) | 273 (78) | 221 (67)* | 150 (69)$ |
| 400–1000 | 17 (4) | 10 (3) | 13 (4) | 5 (2) |
| > 1000 | 361 (93) | 70 (20) | 94 (29)* | 63 (29)$ |
WAZ weight for age, HAZ height for age, WHZ weight for height
* p < 0.05 between baseline and 12 months
$ p < 0.05 between baseline and 24 months by Mcnemar’s test