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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Int J Audiol. 2017 Dec 23;57(SUP4):S89–S98. doi: 10.1080/14992027.2017.1417644

Figure 5.

Figure 5.

Baseline (grey circles) and follow up (black circles) audiogram from an adolescent female undergoing high dose therapy with the loop diuretic, furosemide (Lasix). Ototoxic grading scales that emphasise high-frequency change in hearing (e.g. CTCAE version 4.03 paediatric version) would not be sensitive to capturing this significant decline that occurred early in the course of treatment. The change in hearing was sensorineural (bone conduction data not shown) and bilateral, although data from only a single ear is shown.