Table 3.
Levels of serum ceramides
| Control Group (n = 15) | Sleeve Gastrectomy Group (n = 20) | |||||
|---|---|---|---|---|---|---|
| Ceramide (ng/ml) | Preop | Po Day 1 | Po Day 30 | Preop | Po Day 1 | Po Day 30 |
| C16 CER (d18:1/16:0) | 4107,02 ± 461,12 | 4568,07 ± 265,51 | 4080,22 ± 503,81 | 3397,68 ± 217,02 | 3892,78 ± 401,89 | 3447,04 ± 183,08 |
| C18 CER (d18:1/18:0) | 1312,73 ± 198,25 | 1498,11 ± 144,02 | 1103,22 ± 182,85 | 1188,98 ± 109,14 | 1361,44 ± 203,41 | 1213,58 ± 84,05 |
| C20 CER (d18:1/20:0) | 1062,13 ± 145,50 | 1130,25 ± 125,52 | 983,98 ± 145,01 | 734,67 ± 79,31 | 762,52 ± 158,10 | 650,10 ± 77,73 |
| C22 CER (d18:1/22:0) | 6273,70 ± 851,29 | 6372,18 ± 916,66 | 7144,98 ± 899,62 | 5374,87 ± 440,21 | 3850,60 ± 471,05a,b | 3287,03 ± 371,39c,d |
| C24 CER (d18:1/24:0) | 19,706,45 ± 1892,46 | 22,071,44 ± 3507,56 | 24,340,62 ± 3289,63 | 20,507,48 ± 2366,78 | 14,240,44 ± 1709,18e,f | 12,307,39 ± 1400,13g,h |
Values are mean ± SEM. Preop, preoperation; Po, postoperation. C16 Ceramide (d18:1/16:0), N-palmitoyl-D-erythro-sphingosine; C18 Ceramide (d18:1/18:0), N-stearoyl-D-erythro-sphingosine; C20 Ceramide (d18:1/20:0), N-arachidoyl-D-erythro-sphingosine; C22 Ceramide (d18:1/22:0), N-behenoyl-D-erythro-sphingosine; C24 Ceramide (d18:1/24:0), N-lignoceroyl-D-erythro-sphingosine
a, p = 0,014 vs. sleeve gastrectomy preop. Statistical analysis was done by paired t-test
b, p = 0,008 vs. control Po Day 1. Statistical analysis was done by t-test
c, p < 0,001 vs. sleeve gastrectomy preop. Statistical analysis was done by paired t-test
d, p < 0,001 vs. control Po Day 30. Statistical analysis was done by t-test
e, p = 0,005 vs. sleeve gastrectomy preop. Statistical analysis was done by paired t-test
f, p = 0,022 vs. control Po Day 1. Statistical analysis was done by t-test
g, p < 0,001 vs. sleeve gastrectomy preop. Statistical analysis was done by paired t-test
h, p < 0,001 vs control Po Day 30. Statistical analysis was done by t-test