Table 2.
Variables | HR | Univariate 95% CI |
p | HR | Multivariate 95% CI | p |
---|---|---|---|---|---|---|
OS | ||||||
Age (years) | ||||||
≤ 55 vs. > 55 | 1.002 | 0.965–1.039 | 0.932 | |||
Gender | ||||||
Male vs. female | 0.309 | 0.110–1.868 | 0.076 | |||
Differentiation | ||||||
Good/moderate vs. poor | 0.717 | 0.330–1.558 | 0.401 | |||
pT status | ||||||
pT2–4 vs. pT1 | 3.747 | 1.721–8.160 | 0.001 | 0.580 | ||
pN stage | ||||||
pN1–2 vs. pN0 | 3.090 | 1.569–6.086 | 0.001 | 0.180 | ||
pTNM stage | ||||||
II–III vs. I | 4.921 | 2.629–9.210 | 0.000 | 5.744 | 1.908–17.290 | 0.002 |
miR181b expression | ||||||
Low vs. high | 0.293 | 0.147–0.586 | 0.001 | 0.378 | 0.184–0.775 | 0.008 |
NOTCH2 expression | ||||||
Low vs. high | 1.436 | 1.062–1.941 | 0.019 | 0.242 | ||
CD133 expression | ||||||
Low vs. high | 1.229 | 0.776–1.945 | 0.380 | |||
SOX2 expression | ||||||
Low vs. high | 1.013 | 0.718–1.430 | 0.939 |
CI confidence interval, HR hazard ratio, OS overall survival