Table 4.
Dosimetric parameters of organ at risk with DIBH-TVMAT vs. FB-TVMAT
| DIBH-TVMAT | FB-TVMAT | p-value | ||||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| Heart | mean dose (Gy) | 3.2 | 2.1 | 7.9 | 3.6 | < 0.001 |
| D2% (Gy) | 12.7 | 10.0 | 31.5 | 12.3 | < 0.001 | |
| V30Gy (%) | 0.4 | 1.3 | 3.6 | 4.5 | 0.017 | |
| V10Gy (%) | 4.8 | 7.0 | 25.5 | 14.0 | < 0.001 | |
| V5Gy (%) | 19.4 | 17.8 | 51.5 | 22.4 | < 0.001 | |
| LAD | Dmax (Gy) | 20.1 | 15.3 | 40.4 | 12.3 | 0.001 |
| D10% (Gy) | 17.1 | 15.0 | 36.5 | 13.3 | 0.001 | |
| Left Lung | mean dose (Gy) | 6.6 | 1.9 | 11.8 | 2.1 | < 0.001 |
| D2% (Gy) | 40.1 | 7.5 | 48.4 | 1.8 | < 0.001 | |
| V30Gy (%) | 5.7 | 3.2 | 12.9 | 3.7 | < 0.001 | |
| V20Gy (%) | 9.2 | 4.3 | 20.7 | 4.7 | < 0.001 | |
| V10Gy (%) | 18.7 | 6.0 | 37.6 | 7.2 | < 0.001 | |
| V5Gy (%) | 31.7 | 7.2 | 53.6 | 8.6 | < 0.001 | |
| Right Lung | mean dose (Gy) | 0.7 | 0.3 | 1.5 | 0.6 | < 0.001 |
| D2% (Gy) | 3.7 | 1.4 | 6.8 | 2.2 | < 0.001 | |
| V10Gy (%) | 0.0 | 0.1 | 0.5 | 0.5 | 0.002 | |
| V5Gy (%) | 1.0 | 1.0 | 6.7 | 4.9 | < 0.001 | |
| Right Breast | mean dose (Gy) | 2.0 | 0.6 | 3.4 | 1.3 | 0.001 |
| D2% (Gy) | 7.8 | 2.7 | 9.2 | 3.3 | 0.232 | |
| V10Gy (%) | 1.0 | 1.6 | 2.5 | 2.8 | 0.115 | |
| V5Gy (%) | 9.1 | 6.2 | 24.0 | 11.3 | < 0.001 | |
Legend: Dosimetric parameters of organ at risk (OAR) including heart, left lung, right lung, and breast with tangent-based volumetric modulated arc therapy (TVMAT) under deep inspiration breath-hold (DIBH) technique and free breathing (FB)