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Lipid chain orientational order analysis upon M2AH binding studied using EPR and bicelles. (A) Experimental (solid lines) and simulated (dashed lines) EPR spectra of DMPC/DHPC bicelles containing the spin label 5-SASL. The bilayer normal of the bicelles is aligned parallel to the magnetic field at 308 K. (B) Plot of the orientational order parameter S20 as a function of the P/L ratio. For comparison, the reported values for alamethicin and magainin 2 are also displayed.
