Figure 7.

Ligand molecules in the structure 4hky, with Cd²⁺ ions shown as beige spheres. (A) The original coordinates containing two alternative states of the faropenem ligand. Negative difference density peaks are visible, especially at the unhydrolyzed β-lactam moiety. (B) The original coordinates shown in an omit map after final re-refinement. (C) The final model (6ex7) with a truncated, hydrolyzed version of faropenem. The electron density maps are contoured at 1.0σ for 2mF_o-DF_c (blue) and +/−3.0σ for mF_o-DF_c (green/red). The ligands and the electron density maps, including omit maps, can be inspected using an interactive figure created with Molstack (http://molstack.bioreproducibility.org/project/view/FU0iFwAkG0vsoOtUDZd5/).