Table 2.
Study | Study Design | Subjects number | Radiation dose |
P value | Results and comments | |
---|---|---|---|---|---|---|
WBCTa | SCTb | |||||
Asha et al., 201237 | Retrospective, before/after cohort study. Patients were included 6 months before and after implementation of WBCT protocol. |
Totally 1280 patients; 656 patients before and 624 after the introduction of WBCT protocol | 76c (11.6%) (9.1–14.1) |
122c (19.6%) (16.6–22.7) |
<0.001 | Absolute risk (20%; 95% confidence interval [CI] 17–23) for WBCT of receiving a higher radiation dose (dose ≥20 mSv) was higher when compared with SCT (12%; 95% CI 9–14). |
Gordic et al., 201520 |
Retrospective, before/after cohort study. 120 consecutive patients before and 120 patients after implementation WBCT protocol were included |
240 patients, 120 patients in each protocol group. | 29.5 mSvd | 15.9 mSvd | <0.001 | In the SCT group, additional CT imaging was needed more frequently than in WBCT group with a cumulative dose of 13.0 mSv/patient (p < 0.001). |
Sierink et al., 20167 |
Multi-center, randomized controlled trial. | Totally 1083 patients were included; 541inWBCT, 542in SCT group. | 21 mSvd (20.9–25.2) | 20.6 mSvd (11.8–27.6) | <0.001 | Not only the total radiation exposure was lower in SCT group, but also more patients in this group were exposed to a radiation dose <20 mSv. |
WBCT: whole body computed tomography.
SCT: Selected CT.
number of patients (given as median (%-IQR)) who were exposed radiation dose ≥20 mSv.
The radiation results included all diagnosing tests during hospital admission.