Table 1.

Results of ANOVA and regression analysis of CCD.

Source	Sum of Squares	Mean Square	F Value	p-value	significant
Model	9.34	1.04	197.71	< 0.0001	∗∗∗
X 1	0.25	0.25	48.18	< 0.0001	∗∗∗
X 2	0.031	0.031	5.99	0.0344	∗
X 3	0.34	0.34	63.80	< 0.0001	∗∗∗
X 1 X 2	1.42	1.42	269.92	< 0.0001	∗∗∗
X 1 X 3	0.49	0.49	93.95	< 0.0001	∗∗∗
X 2 X 3	0.050	0.050	9.47	0.0117	∗
X 1 2	2.68	2.68	510.57	< 0.0001	∗∗∗
X 2 2	4.69	4.69	892.45	< 0.0001	∗∗∗
X 3 2	0.28	0.28	52.74	< 0.0001	∗∗∗
Residual	0.053	5.251E-003
Lack of Fit	0.028	5.515E-003	1.11	0.4574	⧫
Pure Error	0.025	4.987E-003
Cor Total	9.40
R-Squared	0.9954
Adj R-Squared	0.9894
Pred R-Squared	0.9454
Adeq Precision	34.815

∗, ∗∗, and ∗∗∗ represent p<0.05, p<0.01, and p<0.0001, respectively.

⧫ represents “not significant”