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. Author manuscript; available in PMC: 2019 Aug 20.
Published in final edited form as: Dev Cell. 2018 Aug 2;46(4):456–469.e4. doi: 10.1016/j.devcel.2018.07.003

Figure 2. Xrp1 does not affect developmental cell death in the retina.

Figure 2.

Panels A-D show pupal retinas labeled for Dlg protein to outline cells (green) and anti-active Dcp1 to reveal apoptotic cell death (magenta). A) 30h after puparium formation (APF). At this stage, apoptosis culls extra cells from the wild type retina. B) Similar cell death occurs in Xrp1−/− mutant retina 30h APF. C) At 43h APF, apoptosis removes cells from the retinal periphery. D) Cell death occurs similarly in Xrp1 mutant retina 43 APF. E) Supernumerary cells were counted 42 h APF to evaluate the efficiency of programmed cell death in the retina. There was no significant increase in supernumerary cells in the Xrp1−/− mutant, indicating that this developmental cell death occurred normally (t-test, p>0.05). Error bars indicate S.E.M. Supplemental data related to this Figure is shown in Table S1.