Table 1.
Clinical and Demographic Features of Sample
| Group | Control (n=140) mean±SD | PTSD (n=142) mean±SD | statistic | p-value |
|---|---|---|---|---|
| Age | 39.2 ± 10.1 | 40.1 ± 10.2 | t = −.806 | .421 |
| Race (AA), n [%] | 61 [43.6] | 61 [43.0] | Χ2 =.69 | .71 |
| female gender; n [%] | 28 [24.3] | 25 [21.0] | Χ2 =.26 | .63 |
| CAPS - Life | 17.2 ± 11.5 | 40.2 ± 10.2 | t = −3.17 | .002 |
| BDI-II | 5.13 ± 7.96 | 17.32 ± 11.51 | t = −10.39 | < .0001 |
| TLEQ | 1.94 ± 2.51 | 4.73 ± 3.28 | t = −8.05 | <.0001 |
| Combat Exposure | 6.29 ± 8.13 | 14.70 ± 11.03 | t = −7.53 | < .0001 |
| Child Trauma (TLEQ) | .39 ± .78 | .85 ± 1.05 | t = −4.15 | < .0001 |
| AUDIT | 2.80 ± 3.32 | 4.32 ± 4.67 | t = −3.18 | .002 |
| Serotonergic n [%] | 4 [2.9] | 52 [36.6] | Χ2 = −7.97 | < .0001 |
| Antipsychotic n [%] | 0 [0] | 4 [2.6] | Χ2 = −2.01 | .05 |
| Mood Stabilizer n [%] | 0 [0] | 2 [1.4] | Χ2 = −.57 | .57 |
| TIV | 1508089 ± 166866 | 1511375 ± 165735 | t = −.17 | .87 |
| GE 3-T MR 750 | 77 (27.3) | 86 (30.5) | Χ2 = 5.56 | .06 |
| GE 3-T EXCITE | 42 (14.9) | 47 (16.7) | NA | NA |
| Philips 3-T Ingenia | 21 (7.4) | 9 (3.2) | NA | NA |
| total hippocampus | 3537 ± 375 | 3480 ± 327 | F=1.96 | .16 |
Abbreviations: SD= Standard Deviation, AA=African American, CAPS = Clinician Administered PTSD Scale, BDI=Beck Depression Inventory, TLEQ=Trauma Life Events Questionnaire, AUDIT = Alcohol Use Disorders Test, TIV=Total Intracranial Volume.