Table 4.
General and biochemical parameters in serum and liver tissues.
| ND | HFD | DHA/EPA = 2 : 1 | DHA/EPA = 1 : 1 | DHA/EPA = 1 : 2 | |
|---|---|---|---|---|---|
| Serum parameters | |||||
| TC (mM) | 9.50 ± 0.46 | 19.38 ± 0.66a | 5.43 ± 0.52a,b | 7.82 ± 0.84b,c | 10.29 ± 0.31b,c,d |
| TG (mM) | 1.19 ± 0.05 | 2.38 ± 0.24a | 0.58 ± 0.05a,b | 0.75 ± 0.08a,b | 1.30 ± 0.07b,c,d |
| LDL (mM) | 3.51 ± 0.19 | 7.03 ± 0.46a | 2.55 ± 0.43b | 4.17 ± 0.40b,c | 4.34 ± 0.17a,b,c |
| HDL (mM) | 0.30 ± 0.03 | 0.13 ± 0.03a | 0.26 ± 0.03a,b | 0.35 ± 0.05b | 0.21 ± 0.01a,b,d |
| Adiponectin (pg/mg) | 159.76 ± 23.19 | 81.64 ± 8.36a | 196.77 ± 18.68b | 114.91 ± 14.16c | 103.97 ± 7.43b,c |
| OX-LDL (μg/L) | 223.46 ± 25.32 | 269.00 ± 14.73 | 171.58 ± 8.58b | 165.90 ± 8.29b | 165.89 ± 10.76a,b |
| AST (U/L) | 143.79 ± 21.97 | 487.5 ± 95.19a | 63.62 ± 7.36a,b | 110.23 ± 13.31b,c | 138.32 ± 28.99b,c |
| ALT (U/L) | 72.92 ± 9.06 | 210.82 ± 23.72a | 40.69 ± 4.88a,b | 51.67 ± 3.05a,b | 93.06 ± 13.03b,c,d |
| AKP (U/L) | 48.94 ± 5.18 | 90.66 ± 7.22a | 42.08 ± 3.50b | 58.93 ± 5.92b,c | 70.34 ± 4.55a,b,c |
| Liver parameters | |||||
| TC (mM/g protein) | 74.94 ± 3.62 | 144.57 ± 4.72a | 73.81 ± 4.22b | 83.72 ± 3.30b,c | 77.59 ± 6.03b |
| TG (mM/g protein) | 204.01 ± 25.74 | 231.19 ± 14.54 | 125.21 ± 14.26a,b | 114.81 ± 7.32a,b | 160.34 ± 15.76 |
| MDA (μM/g protein) | 1.75 ± 0.17 | 2.31 ± 0.18a | 1.81 ± 0.14b | 1.73 ± 0.07b | 1.90 ± 0.08 |
| SOD (U/mg protein) | 6.2 ± 0.32 | 5.79 ± 0.16 | 6.9 ± 0.14b | 6.85 ± 0.03a,b | 6.86 ± 0.26b |
| GSH (μM/g protein) | 19.46 ± 2.37 | 10.8 ± 1.57a | 21.9 ± 2.59b | 23.81 ± 1.86b | 24.33 ± 2.69b |
Data are given as mean ± SEM, n = 8. aP < 0.05 versus the ND group; bP < 0.05 versus the HFD group; cP < 0.05 versus the DHA/EPA = 2 : 1 group; dP < 0.05 versus the DHA/EPA = 1 : 1 group.