Table 3.
Fetal intrauterine functional connectivity relates to higher infant motor function in structural equation models accounting for sex, movement during the scan, and salient maternal characteristics
Fetal cerebellar functional connectivity | B | SE | β | p |
---|---|---|---|---|
Gender | −4.32 | 2.99 | −0.15 | .161 |
Motion | 19.64 | 11.52 | 0.14 | .086 |
Maternal education | −0.60 | 1.04 | −0.04 | .570 |
Income | −0.35 | 0.48 | −0.06 | .464 |
Prenatal anxiety | −0.05 | 0.52 | −0.01 | .918 |
Cerebellum functional connectivity | 8.47 | 3.22 | 0.37 | .003 |
Cerebellum Functional Connectivity × Gender | −8.29 | 4.08 | −0.24 | .030 |
Fetal anterior cingulate cortex (ACC) functional connectivity | ||||
Gender | −3.98 | 2.92 | −0.14 | .183 |
Motion | 11.88 | 11.33 | 0.09 | .302 |
Maternal education | −1.62 | 1.15 | −0.12 | .171 |
Income | −0.32 | 0.42 | −0.05 | .458 |
Prenatal anxiety | 0.05 | 0.43 | 0.01 | .905 |
ACC functional connectivity | −8.51 | 3.28 | −0.44 | <.001 |
ACC Functional Connectivity × Gender | 3.86 | 4.04 | 0.13 | .301 |
Fetal prefrontal cortex (PFC) functional connectivity | ||||
Gender | −4.58 | 2.81 | −0.14 | .109 |
Motion | 18.18 | 10.39 | 0.12 | .074 |
Maternal education | −1.59 | 1.47 | −0.11 | .308 |
Income | −0.32 | 0.47 | −0.05 | .498 |
Prenatal anxiety | −0.37 | 0.51 | −0.07 | .446 |
PFC functional connectivity | 12.32 | 3.13 | 0.48 | <.001 |
PFC Functional Connectivity × Gender | −11.94 | 4.30 | −0.35 | .002 |
Fetal inferior parietal lobule (IPL) functional connectivity | ||||
Gender | −4.31 | 3.02 | −0.15 | .16 |
Motion | 15.25 | 11.46 | 0.11 | .18 |
Maternal education | −0.19 | 1.10 | −0.02 | .86 |
Income | −0.20 | 0.43 | −0.03 | .64 |
Prenatal anxiety | −0.32 | 0.52 | −0.06 | .53 |
IPL functional connectivity | 4.74 | 1.36 | 0.30 | <.001 |
IPL Functional Connectivity × Gender | −2.79 | 2.41 | −0.12 | .240 |
Note: Connectivity of the ACC negatively predicts motor outcome; all other regions are positively related to infant motor ability at 7 months.