Table 2.
Effect of ester modification of 4-(3-bromophenyl) 1,4-DHPs on Notch inhibition. fx
 |
| Compound Number |
R2 | IC50 (μM) |
|---|---|---|
| 6 |  |
4.15 |
| 7 |  |
0.36 |
| 8 |  |
2.95 |
| 9 |  |
>10 |
| 10 |  |
0.86 |
| 11 |  |
4.27 |
| 12 |  |
> 10 |
| 13 |  |
> 10 |
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