Table 1. The number of differentially expressed biotypes in HS294T and SKMEL-2 cell lines.

Cell lines	Total n. of differentially expressed biotypes		Cell-specific differentially expressed biotypes
HS294T	1536		808
SKMEL-2	1993		1265
Number of shared differentially expressed biotypes		728

Note: The DE biotypes were selected based on criteria involving both expression and methylation levels in the treatment group, i.e. threshold of logFC > 50% quartile of logFC values, and hyper-methylation at the promoter of unregulated DE values.