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. 2018 Nov 28;13(11):e0207228. doi: 10.1371/journal.pone.0207228

Fig 2. CCN5 KO mice exhibit mild type 2 diabetes.

Fig 2

(A) Blood glucose levels during the 24 weeks of NCD or HFD feeding (mean data collected from 3 independent experimental sets, n = 6–12 per group for each experimental set). (B) Fasting blood glucose levels in each group after 16 h of nocturnal fasting (mean data collected from 3 independent experimental sets, n = 6–12 per group for each experimental set). (C) Plasma adiponectin levels in each group (n = 4 for NCD group, n = 6 for HFD group). (D) ITT and GTT after 11 weeks of NCD or HFD feeding (n = 8–9 per group for each group). Plasma insulin levels after 12 weeks of NCD or HFD feeding (n = 7 per group). (E) ITT and GTT after 23 weeks old NCD or HFD feeding (mean data collected from 3 independent experimental sets, n = 6–8 per group for each experimental set). Plasma insulin levels after 24 weeks of NCD or HFD feeding (n = 7–8 per group). Data are presented as mean ± SD. *p<0.05, **p<0.01 vs. WT.