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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Transgenic Res. 2018 Oct 4;27(6):489–509. doi: 10.1007/s11248-018-0096-8

Figure 5.

Figure 5.

dCas9 conjugation approach to recruit endogenous chromatin regulators to specific genomic loci. Fkbp/Frb dimerizing induced proximity of the Frb-chromatin regulator to dCas9-MS2-Fkbp upon rapamycin (RAP) treatment.