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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Mol Neurobiol. 2018 May 28;56(2):954–962. doi: 10.1007/s12035-018-1137-2

Fig. 4. The effects of 4-aminobenzoic acid hydrazide (ABAH) on MMP+ cells.

Fig. 4

a Cell surface markers used to subdivide cells into various subsets of leukocytes in the brain of saline-treated control and ABAH-treated EAE mice 12 days after immunization. Numbers denote percent MMP-positive cells in saline (34%± 5%) versus ABAH group (15%±3%) (P=0.009, n=5 per group, two-tailed student t-test) (Red line: percent MMP-positive cells in sham mice; Blue line: percent MMP-positive cells in EAE mice). b Total MMP positive cell counts in brain. There are significant differences between saline and ABAH group in cell number of microglia/monocytes/macrophages and neutrophils (Mann-Whitney test, **P = 0.007 and **P = 0.04). c Contribution of cell types to MMP activity in EAE based on results in a and b. MMP=matrix metalloproteinase.