Examples of biomaterials and their routes of administration for in vivo use. In addition to pills and injections, biomaterials have been developed to successfully administer drugs in a variety of other ways. Images for ocular delivery: left: Reproduced with permission.[150b] Copyright 2014, American Chemical Society; right: reproduced with permission.[237a] Copyright 2014, Elsevier. Images for buccal delivery: reproduced with permission.[237e] Copyright 2015, Elsevier. Images for pulmonary delivery: left: reproduced with permission.[12e] Copyright 1997, American Association for the Advancement of Science; right: reproduced with permission.[237f] Copyright 2009, Springer Science. Images for systemic delivery: reproduced with permission.[237d] Copyright 2016, National Academy of Sciences, USA. Images for surgical implantation: left: reproduced with permission.[237b] copyright 2002, Adis International; right: reproduced with permission.[237c] Copyright 1998, Elsevier. Images for oral delivery: reproduced with permission.[237g] Copyright 2016, American Association for the Advancement of Science. Images for transdermal delivery: reproduced with permission.[170j] Copyright 2015, National Academy of Sciences, USA. Images for vaginal delivery: reproduced with permission.[237h] Copyright 2017, Elsevier.