Table 1.
Characteristics of the patients investigated in the study
| Patient number | Age | PSA | Gleason score | Previous therapy | Other metastases | Therapy change after imaging | SUVaverage | SUVmax | Slope | Intercept |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 72 | 1.86 | 8 | Radical prostatectomy and radiation therapy | Yes (bone) | Yes (radiation therapy and androgen deprivation therapy) | 6.2 | 7.5 | Positive | Positive |
| 2 | 76 | 2.35 | 6 | Radical prostatectomy and radiation therapy | No | Yes (Salvage-HIFU) | 4.6 | 4.7 | Positive | Positive |
| 3 | 70 | 0.27 | 7 | Radical prostatectomy and lymphadenectomy | Yes (lymph nodes) | Yes (Salvage radiation therapy to the prostatic fossa and pelvic nodes) | 45.8 | 50.9 | Positive | Positive |
| 4 | 57 | 1.98 | Unknown | Radical prostatectomy | No | Yes (8 months later radiation therapy by persistent PSA increase; no other imaging after 68Ga-PSMA PET/CT) | 10.7 | 12.3 | Positive | Positive |
| 5 | 72 | 2.00 | 9 | HDR brachytherapy | Yes (lymph nodes) | Yes (TURP after 6 months; no other imaging after 68Ga-PSMA PET/CT) | 6.4 | 7.4 | Positive | Positive |
| 6 | 77 | 19.90 | 7 | HIFU | Yes (lymph nodes, bone) | Yes (androgen deprivation therapy) | 5.2 | 5.5 | Positive | Positive |
| 7 | 67 | 6.77 | 8 | Radiation therapy | No | No | 7.9 | 10.2 | Positive | Positive |
| 8 | 59 | 7.18 | Unknown | Radiation therapy | No | No | 3.1 | 3.3 | Positive | Positive |
| 9 | 69 | 1.20 | 9 | Radiation therapy | No | Yes (Salvage-HIFU) | 29.8 | 37.6 | Positive | Positive |
| 10 | 64 | 3.40 | 7 | Radiation therapy | No | Yes (Salvage-HIFU) | 12.7 | 13.1 | Positive | Positive |
| 11 | 60 | Unknown | Unknown | Radical prostatectomy | Local recurrence is static PET/CT-negative and MRI-positive. No other lesions | Yes (Salvage radiation therapy) | n.a. | n.a. | Negative | Negative |
| 12 | 68 | 4.17 | Unknown | Radical prostatectomy and HIFU | No | Yes (HIFU) | 26.5 | 29.0 | Positive | Positive |
| 13 | 69 | 11.66 | 7 | Radical prostatectomy | Yes (lymph nodes) | Yes (androgen deprivation therapy after 9 months; no other imaging after 68Ga-PSMA PET/CT) | 14.5 | 27.2 | Positive | Positive |
| 14 | 73 | 4.60 | 7 | Radical prostatectomy | Local recurrence is static PET/CT-negative and MRI-positive. No other lesions | Yes (androgen deprivation therapy; radiation therapy recommended, but declined from the patient) | n.a. | n.a. | Negative | Negative |
| 15 | 78 | 2.02 | 9 | Radical prostatectomy | Local recurrence is static PET/CT-negative and MRI-positive. Lymph nodes and bone metastases | Yes (androgen deprivation therapy) | n.a. | n.a. | Negative | Negative |
| 16 | 71 | 0.18 | 10 | Radical prostatectomy and lymphadenectomy | Local recurrence is static PET/CT-negative and MRI-positive. Lymph nodes and bone metastases | Yes (radiation therapy and androgen deprivation therapy) | n.a. | n.a. | Negative | Positive |
HDR, high-dose rate; HIFU, High intensity focused ultrasound; TURP, transurethral resection of the prostate; n.a., not applicable.