Fig. 4.

Mechanism of action of phytochemicals involving non-coding RNA regulations within breast carcinogenesis. See text for indicated changes as each displayed axis represents the findings of presented studies. Arrows demonstrate specific effect of phytochemicals in female breast cancer model; ↑induction/upregulation, ↓inhibition/reduction. DNMT3b, DNA(cytosine-5-)-methyltransferase 3 beta; Mcl-1, induced myeloid leukemia cell differentiation protein; PTEN, phosphatase and tensin homolog; TIGAR, TP53-inducible glycolysis and apoptosis regulator; T-S, tumor-suppressive