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. 2018 Nov 22;9:1343. doi: 10.3389/fphar.2018.01343

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Copyright © 2018 Ye, Duan, Deng, Wang, Chen, Cui, Sun, Zhang, Du, Gu, Lin and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of DENND1A affects the prognosis of patients with gastric cancer. (A,B) The expression of DENND1A was analyzed by immunohistochemistry in normal gastric tissue and gastric cancer tissue (n = 20). (C) The expression of DENND1A was analyzed by GEO database in normal gastric tissue and gastric cancer tissue (n = 90). (D) Kaplan-Meier survival plots demonstrating the poor prognostic effect of DENND1A gene high expression correlated with a short RFS in gastric cancer patients (n = 432). All data are log transformed and median centered (^∗∗∗P < 0.001).