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. 2018 Nov 22;9:1371. doi: 10.3389/fphar.2018.01371

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Copyright © 2018 Sui, Zhang, Liu, Duan, Zhai, Zhang, Han, Xiang, Huang, Lin and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ferroptosis contributes to RSL3-induced growth inhibition in CRC cells. (A) HCT116 cells were treated with RSL3 with or without the indicated inhibitors for 24 h and cell viability was assayed (n = 3, ^∗p < 0.05 versus RSL3 treatment group); (B) HT29 cells were treated with RSL3 with or without the indicated inhibitors for 24 h and cell viability was assayed (n = 3, ^∗p < 0.05 versus RSL3 treatment group). (C) LoVo cells were treated with RSL3 with or without the indicated inhibitors for 24 h and cell viability was assayed (n = 3, ^∗p < 0.05 versus RSL3 treatment group).