Table 5.
Groups | Correction factors | Rank | BUN | sCRE | uCRE | |||
---|---|---|---|---|---|---|---|---|
All (NR, KD) | Raw, uRNA, uCRE | 1 | let-7b | −0.589** | let-7b | −0.596** | let-7b | 0.230* |
2 | let-7b/uRNA | −0.470** | miR-22 | −0.482** | NA | |||
3 | miR-22 | −0.460** | let-7b/uRNA | −0.460** | NA | |||
4 | miR-22/uRNA | −0.425** | miR-22/uRNA | −0.438** | NA | |||
5 | miR-26a | −0.344** | miR-21a/uCRE | 0.352** | NA | |||
6 | miR-21a/uCRE | 0.341** | miR-26a | −0.295** | NA | |||
7 | miR-191 | −0.291** | miR-191 | −0.294** | NA | |||
8 | miR-10b | −0.286** | miR-191/uRNA | −0.246* | NA | |||
KD | Raw, uRNA, uCRE | 1 | NA | miR-181a | 0.351* | NA | ||
All(NR, KD) | Ratio | 1 | miR-21a/let-7b | 0.754** | miR-21a/let-7b | 0.751** | let-7b/miR-21a | 0.421** |
2 | miR-21a/miR-22 | 0.557** | miR-21a/miR-22 | 0.614** | let-7b/miR-10a | 0.332** | ||
3 | let-7f/let-7b | 0.522** | miR-10a/let-7b | 0.547** | let-7b/miR-486 | 0.259* | ||
4 | miR-486/miR-22 | 0.475** | let-7f/let-7b | 0.524** | let-7b/miR-22 | 0.252* | ||
5 | miR21a/miR-26a | 0.471** | miR-21a/miR-191 | 0.473** | miR-27b/miR-10a | 0.231* | ||
KD | Ratio | 1 | miR-21a/let-7b | 0.440* | miR-21a/let7b | 0.601** | miR-26a/miR-191 | 0.318* |
2 | miR-181a/let-7b | 0.420* | miR-181a/miR-10b | 0.571** | NA | |||
3 | miR-181a/miR-10b | 0.333* | miR-181a/let-7b | 0.568** | NA | |||
4 | NA | miR-181a/let-7f | 0.505** | NA | ||||
5 | NA | miR-181a/miR-10a | 0.445** | NA |
NR, normal renal function group; KD, kidney disease group; sCRE, serum creatinine; BUN, blood urea nitrogen; uCRE, urinary creatinine; NA, not available.
Spearman's correlation test (P < 0.05, P < 0.01) was used to analyze the correlation between two parameters