Table 3. Factors related with INR control (n = 852).
| Characteristics | WC | PC | P value | |
|---|---|---|---|---|
| Sex, male | 131 (58.0) | 381 (60.9) | 0.4457a | |
| Age, yr | 71.77 (7.78) | 66.20 (10.42) | < 0.0001b | |
| BMI | 24.69 (3.32) | 24.87 (3.29) | 0.5242b | |
| NVAF duration, mon | 21.03 (40.42) | 17.44 (31.59) | 0.8384c | |
| Type of NVAF | 0.8887a | |||
| First diagnosed | 27 (12.0) | 65 (10.4) | ||
| Paroxysmal | 68 (30.1) | 195 (31.2) | ||
| Persistent | 85 (37.6) | 250 (39.9) | ||
| Long-standing persistent | 13 (5.8) | 30 (4.8) | ||
| Permanent | 24 (10.6) | 56 (9.0) | ||
| Unknown | 9 (4.0) | 30 (4.8) | ||
| Mental co-morbid conditions, yes | 14 (6.2) | 25 (4.0) | 0.1747a | |
| Employment, yes | 56 (24.9) | 247 (39.7) | < 0.0001a | |
| Alcohol use | 0.0775a | |||
| Non-drinker | 111 (49.1) | 256 (40.9) | ||
| Past drinker | 55 (24.3) | 162 (25.9) | ||
| Current drinker | 60 (26.6) | 208 (33.2) | ||
| Smoking | 0.0577a | |||
| Non-smoker | 140 (62.0) | 356 (56.9) | ||
| Past smoker | 74 (32.7) | 204 (32.6) | ||
| Current smoker | 12 (5.3) | 66 (10.5) | ||
| Education | 0.9384a | |||
| No education | 18 (8.0) | 48 (7.8) | ||
| ≤ Elementary school | 52 (23.1) | 157 (25.4) | ||
| ≤ Middle school | 34 (15.1) | 94 (15.2) | ||
| ≤ High school | 62 (27.6) | 173 (28.0) | ||
| ≤ University | 47 (20.9) | 123 (19.9) | ||
| ≥ Post-graduation school | 12 (5.3) | 24 (3.9) | ||
| CHADS2 score | 1.92 (0.89) | 1.83 (0.97) | 0.0637c | |
| CHA2DS2-VASc score | 3.21 (1.21) | 2.85 (1.43) | 0.0002b | |
| HAS-BLED score | 1.41 (0.63) | 1.52 (0.66) | 0.0292c | |
| VKA dosage, mg/day | 19.51 (7.61) | 19.36 (9.84) | 0.8190b | |
| VKA treatment | 0.0003a | |||
| Continue | 189 (83.6) | 446 (71.3) | ||
| Discontinued & switching | 22 (9.7) | 446 (71.3) | ||
| Discontinued & no switching | 15 (6.6) | 44 (7.0) | ||
Data are presented as mean (standard deviation) or number (%).
INR = international normalized ratio, WC = well-controlled, PC = poor-controlled, BMI = body mass index, NVAF = non-valvular atrial fibrillation, VKA = vitamin K antagonist.
aP value calculated by χ2 test; bP value calculated by Student's t-test; cP value calculated by Mann-Whitney's U test.