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. 2018 Nov 28;3(6):e00478-18. doi: 10.1128/mSphere.00478-18

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Copyright © 2018 Ichikawa et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 4 — Prominent decrease in H3K27me3 modification in EZH2-KO cells. (A to C) WT and EZH2-KO Akata cells latently infected with EBV (cl1) were subjected to chromatin immunoprecipitation (ChIP) analysis using normal IgG (A), anti-histone H3 (B), or anti-histone H3K27me3 (C) antibodies. Data for normal IgG and histone H3 are shown as the percentage of the input sample. Data for H3K27me3 (C) are shown after normalization to the value of histone H3. Lp, LMP1 promoter; Qp, Q promoter; Cp, C promoter; Zp, BZLF1 promoter; Mp, BMRF1 promoter; Ap, BALF2 promoter; Globinp, globin promoter; GAPDHp, GAPDH promoter. Student’s t test was performed. *, P < 0.01.