Figure 1.

Description of the three interventions: (a) standard cardiopulmonary bypass (CPB) without perfusion of the pulmonary circuit; (b) CPB plus continuous pulmonary artery perfusion with normothermic oxygenated blood (400 mL/min); (c) CPB plus pulmonary artery perfusion with a single-shot of histidine-tryptophan-ketoglutarate (HTK) solution (2000 mL). The volume returning to the left atrium from the pulmonary circuit was filtered by a cell saver, only returning the red blood cells to the heart and lung machine’s venous reservoir. At the end of CPB, reperfusion of the pulmonary circuit added approximately 500 mL HTK solution to the systemic circuit.